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Crystal Mackall
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Journal Articles

Superior efficacy and persistence of Orca-T-allogeneic CAR19/22 versus autologous CAR19/22 in high-risk adult B-ALL

Free
Alfonso Molina, Parveen Shiraz, Alyssa Kanegai, Ayesha Fraser, Diana Kordek, Caroline Wagner, Hrishikesh Srinagesh, Lindsay Danley, Arvind Ramakrishnan, Hossein Daghagh, Ying-Wen Huang, Gaurav Dhapola, Aman Siddiqui, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hany Elmariah, Matthew Frank, Hitomi Hosoya, Vanessa Kennedy, Laura Johnston, Everett Meyer, Lekha Mikkilineni, Robert Lowsky, Robert Negrin, Andrew Rezvani, Judith Shizuru, Surbhi Sidana, Wen-Kai Weng, Catherine McIntyre, Steven Feldman, Bita Sahaf, Crystal Mackall, David Miklos, Lori Muffly, Melody Smith
Journal: Blood
Blood (2025) 146 (Supplement 1): 514.
https://doi.org/10.1182/blood-2025-514
Published: 2025
Journal Articles

Redefining post-CD19 CAR T-cell surveillance with ctdna: Real-world insights from post- axi-cel and liso-cel therapy

Free
Snegha Ananth, Jayasindhu Mallampet, Betty Chang, Neha Agarwal, Katherine Kong, Bita Sahaf, Juan Carlos Suarez Serrato, Ilan Kirsch, Allison Jacob, Heidi Simmons, Lik Wee Lee, Crystal Mackall, Wen-Kai Weng, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, David Miklos, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 941.
https://doi.org/10.1182/blood-2025-941
Published: 2025
Journal Articles

Pre-CAR next generation sequencing informs patient outcomes in children and young adults with B-acute lymphoblastic leukemia

Free
Rohaum Hamidi, Amy Zhang, Malka Handwerker, Dhruv Bhatt, Kara Davis, Sneha Ramakrishna, Catherine Aftandilian, Jennifer Moon, Ashley Jacobs, Emily DeYager, Courtney Erickson, Divya Madhav, Regina Dagher, Crystal Mackall, Tanja Gruber, Christina Baggott, Lik Wee Lee, Ilan Kirsch, Liora Schultz
Journal: Blood
Blood (2025) 146 (Supplement 1): 550.
https://doi.org/10.1182/blood-2025-550
Published: 2025
Journal Articles

Double-dose axicabtagene ciloleucel (Axi-Cel-2) as second-line therapy for high-risk relapsed or refractory large B-cell lymphoma (r/rLBCL): Interim results from a Phase 1b study

Free
Dasom (Caroline) Lee, Kameron Rodrigues, Masooma Rana, Kendall Kozy, Sunny Salazar, Alexandria Jensen, Moksha Desai, Jayasindhu Mallampet, Claire Lohman, Ying-Wen Huang, Xiaoman Kang, Feng Tian, Jurik Mutter, Nick Phillips, Colleen Schweitzer, Faisal Cheema, Lekha Mikkilineni, Andrew Rezvani, Laura Johnston, Judith Shizuru, Everett Meyer, Robert Lowsky, Wen-Kai Weng, Melody Smith, Sushma Bharadwaj, Robert Negrin, Surbhi Sidana, Lori Muffly, Bita Sahaf, Yasodha Natkunam, Rhine Shen, Matthew Frank, Crystal Mackall, Zinaida Good, Ash Alizadeh, David Miklos, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 671.
https://doi.org/10.1182/blood-2025-671
Published: 2025
Journal Articles

Overlap of post-CAR T HLH toxicity definitions and their prognostic significance in children and young adults with B-acute lymphoblastic leukemia

Free
Kevin McNerney, Soyang Kwon, Swati Naik, Vanessa Fabrizio, Gabriela Llaurador Caraballo, Lazaro Sanchez-Pinto, Aimee Talleur, Xiaopei Lily Zeng, Christina Baggott, Anant Vatsayan, Michael Verneris, Snehit Prabhu, Jenna Rossoff, Holly Pacenta, Christine Phillips, Julie-An Talano, Amy Moskop, Douglas Myers, Nicole Karras, Challice Bonifant, Muna Qayed, Prakash Satwani, William Temple, Christa Krupski, Amy Keating, Susanne Baumeister, Emily Egeler, Sharon Mavroukakis, Kevin Curran, Crystal Mackall, Theodore Laetsch, Rebecca Gardner, Liora Schultz
Journal: Blood
Blood (2025) 146 (Supplement 1): 4501.
https://doi.org/10.1182/blood-2025-4501
Published: 2025
Journal Articles

Peripheral blast count at apheresis as a risk factor for survival following tisagenlecleucel in children and young adults

Free
Kaylyn Lyons, Kristen Miller, Arpita Deb, Andrew Nicklawsky, Christina Baggott, Khanh Nguyen, Snehit Prabhu, Holly Pacenta, Christine Phillips, Jenna Rossoff, Heather Stefanski, Julie-An Talano, Amy Moskop, Amy Keating, Susanne Baumeister, Douglas Myers, Nicole Karras, Stacy Cooper, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Vasant Chinnabhandar, Crystal Mackall, Samuel John, Theodore Laetsch, Kevin Curran, Michael Verneris, Liora Schultz, Vanessa Fabrizio
Journal: Blood
Blood (2025) 146 (Supplement 1): 7638.
https://doi.org/10.1182/blood-2025-7638
Published: 2025
Journal Articles

Sequential CD19 and CD22 CART for relapsed and refractory B cell ALL: Phase I results

Free
Liora Schultz, Catherine Aftandilian, Christina Baggott, Nicole Corwin, Michelle Fujimoto, Amy Li, Sharon Mavroukakis, Jennifer Moon, Bita Sahaf, Ashley Jacobs, Emily DeYager, Cristina Mendoza, Andrea Levenson, Matthew Frank, David Miklos, Lori Muffly, Steven Feldman, Janette Alcazar, Ramya Tunuguntla, Annie Brown, Raya Saab, Jay Balagtas, Tanja Gruber, Pablo Domizi, Sneha Ramakrishna, Crystal Mackall, Kara Davis
Journal: Blood
Blood (2025) 146 (Supplement 1): 2374.
https://doi.org/10.1182/blood-2025-2374
Published: 2025
Journal Articles

CD22-CAR T cell multiomic features linked to patient outcomes in CD19-CAR resistant large B cell lymphoma

Free
Anne Marijn Kramer, Tara Murty, Yiyun Chen, Kameron Rodrigues, Mark Hamilton, Moksha Desai, Adam Kuo, Zachary Ehlinger, Warren Reynolds, Hrishikesh Srinagesh, Kristin Tsui, Skyler Rietberg, Kelvin Mo, John Baird, Yi-Jiun Su, Neha Agarwal, Elena Sotillo, Snehit Prabhu, Bita Sahaf, Saurabh Dahiya, Sneha Ramakrishna, Lori Muffly, Crystal Mackall, David Miklos, Zinaida Good, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 566.
https://doi.org/10.1182/blood-2025-566
Published: 2025
Journal Articles

Pre-treatment CD19 antigen density and multi-antigen profiling by calibrated quantitative flow cytometry correlates with CAR T efficacy in LBCL

Free
Jay Spiegel, Jean Oak, Masooma Rana, Alexandria Jensen, Dasom (Caroline) Lee, Sao-Mai Nguyen-Mau, Katherine Kong, Scott Bornheimer, Lekha Mikkilineni, Lori Muffly, Surbhi Sidana, Wen-Kai Weng, Sushma Bharadwaj, Melody Smith, Matthew Frank, Rhine Shen, Crystal Mackall, Yasodha Natkunam, David Miklos, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 5882.
https://doi.org/10.1182/blood-2025-5882
Published: 2025
Journal Articles

Pre-transplant CAR T-cell therapy is associated with inferior survival and increased non-relapse mortality in pediatric B-ALL: A single-center retrospective analysis

Free
Rozalyn Chok, Minxuan Huang, Catherine Aftandilian, Liora Schultz, David Shyr, Norman Lacayo, Ami Shah, Raya Saab, Tanja Gruber, Crystal Mackall, Alice Bertaina, Kara Davis, Orly Klein
Journal: Blood
Blood (2025) 146 (Supplement 1): 6077.
https://doi.org/10.1182/blood-2025-6077
Published: 2025
Journal Articles

CD22-directed CAR-T cells induce complete remissions in high-risk follicular and Mantle Cell Lymphoma with limited neurotoxicity

Free
Hrishikesh Srinagesh, Anne Marijn Kramer, Mark Hamilton, Yi-Jiun Su, Kendall Kozy, LaTesha Jackson, Annie Brown, Kimi DeNoble, Sharon Mavroukakis, Claire Lohman, Kristen Cunanan, Neha Agarwal, Sushma Bharadwaj, Warren Reynolds, Sally Arai, Laura Johnston, Robert Lowsky, Everett Meyer, Robert Negrin, Andrew Rezvani, Judith Shizuru, Lekha Mikkilineni, Hitomi Hosoya, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa Kennedy, Melody Smith, Saurabh Dahiya, Kara Davis, Sneha Ramakrishna, Liora Schultz, Ramya Tunuguntla, Lori Muffly, Crystal Mackall, David Miklos, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 4159.
https://doi.org/10.1182/blood-2025-4159
Published: 2025
Journal Articles

Attention-based multiple instance learning predicts CAR T cell therapy outcomes from infusion product single-cell RNA-seq data and identifies engineering targets in large B cell lymphoma

Free
Kameron Rodrigues, Kristin Tsui, Xianghao Zhan, Yiyun Chen, Kelvin Mo, Crystal Mackall, David Miklos, Olivier Gevaert, Zinaida Good
Journal: Blood
Blood (2025) 146 (Supplement 1): 5897.
https://doi.org/10.1182/blood-2025-5897
Published: 2025
Journal Articles

A phase 1 clinical trial of NKTR-255 with CD19-22 CAR T-cell therapy for refractory B-cell acute lymphoblastic leukemia

Free
Clinical Trials & Observations
Hrishikesh Srinagesh, Clayton Jackson, Parveen Shiraz, Nikeshan Jeyakumar, Mark Hamilton, Emily Egeler, Sharon Mavroukakis, Adam Kuo, Juancarlos Cancilla, Bita Sahaf, Neha Agarwal, Alyssa Kanegai, Anne Marijn Kramer, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hitomi Hosoya, Laura Johnston, Vanessa Kennedy, Michaela Liedtke, Robert Lowsky, Lekha Mikkilineni, Robert Negrin, Andrew Rezvani, Surbhi Sidana, Judith Shizuru, Melody Smith, Wen-Kai Weng, Steven Feldman, Matthew J. Frank, Zachary Lee, Mary Tagliaferri, A. Mario Marcondes, David Miklos, Crystal Mackall, Lori Muffly
Journal: Blood
Blood (2024) 144 (16): 1689–1698.
https://doi.org/10.1182/blood.2024024952
Published: 2024
Includes: Supplemental data
Journal Articles

A Highly Efficient Method to Expand CD3 - CD56 + NK Cells from Cord Blood Segments

Free
Sumithira Vasu, Maria Berg, Andreas Lundqvist, Muthalagu Ramanathan, Rebecca Lopez, Phil McCoy, Jr, Hua Zhang, Crystal Mackall, Richard Childs
Journal: Blood
Blood (2008) 112 (11): 3902.
https://doi.org/10.1182/blood.V112.11.3902.3902
Published: 2008
Journal Articles

Elevated Serum Interleukin-7 Levels Precede the Development of Acute Graft-Versus-Host Disease.

Free
Robert M. Dean, MD, Terry Fry, MD, Crystal Mackall, MD, Seth M. Steinberg, PhD, Frances T. Hakim, PhD, Daniel H. Fowler, MD, Jeanne Odom, RN, Jason Foley, MS, Ronald E. Gress, MD, Michael R. Bishop, MD
Journal: Blood
Blood (2007) 110 (11): 1064.
https://doi.org/10.1182/blood.V110.11.1064.1064
Published: 2007
Journal Articles

Interleukin-7 Produced by Antigen Presenting Cells Regulates the Homeostatic Peripheral Expansion of Naive CD4 T Cells.

Free
Martin Guimond, PhD, Rachelle G. Veenstra, BA, David J. Grindler, BA, Yongzi Cui, MD/PhD, Risu Na, PhD, Lothar Hennighausen, PhD, Hua Zhang, PhD, Melinda S. Merchant, MD/PhD, Crystal Mackall, MD
Journal: Blood
Blood (2007) 110 (11): 1333.
https://doi.org/10.1182/blood.V110.11.1333.1333
Published: 2007
Journal Articles

IL7 Administration in Humans Results in Preferential Expansion of Naive and Memory CD4+ & CD8+ T Cells with a Relative Decrease in Regulatory T-Cells (T-Regs).

Free
Claude Sportes, MD, Michael Krumlauf, RN, Rebecca Babb, RN, Ladan Foruraghi, RN, Janine Daub, RN, Daniele Avila, RN, Catherine Chow, MD, Hua Zhang, PhD, Kevin Chua, PhD, Terry Fry, MD, Sarfraz Memon, PhD, Frances Hakim, PhD, Thomas Fleisher, MD, Margaret Brown, BSN, Julie Engel, PhD, Renaud Buffet, MD, Michel Morre, DVM, Ronald Gress, MD, Crystal Mackall, MD
Journal: Blood
Blood (2006) 108 (11): 871.
https://doi.org/10.1182/blood.V108.11.871.871
Published: 2006
Journal Articles

Subclinical GVHD Impairs Responses to Dendritic Cell Vaccines Following Allogeneic Transplantation.

Free
Sarah Herby, Matthew Milliron, Crystal Mackall, MD, Terry Fry, MD
Journal: Blood
Blood (2005) 106 (11): 571.
https://doi.org/10.1182/blood.V106.11.571.571
Published: 2005
Journal Articles

Evaluation of the CD8+ Tumor Associated vs. Non-Tumor Associated Immune Repertoire in Cancer Patients Following Induction of Lymphopenia and Following CD3/4-1BB Based Expansion.

Free
Kristen Snyder, MD, Hua Zhang, PhD, Barbara Vance, PhD, Carl H. June, MD, Robert Vonderheide, MD, PhD, Crystal Mackall, MD
Journal: Blood
Blood (2005) 106 (11): 2390.
https://doi.org/10.1182/blood.V106.11.2390.2390
Published: 2005