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Journal Articles

Risk factors and outcomes of asparaginase-associated pancreatitis in pediatric patients with ALL

Blood (2025) 146 (20): 2417–2427.

https://doi.org/10.1182/blood.2025029785

Published: 2025

Includes: Supplemental data

Journal Articles

PI3Kδ inhibition enhances trametinib efficacy by suppressing feedback-activated PI3K/AKT signaling in PTPN11-mutant JMML

Yuming Zhao, Yao Guo, Zhiyong Peng, Tianqi Liang, Zhiguang Chang, Yan Xiao, Dengyang Zhang, Liuting Yu, Lingling Ma, Chi Kong Li, Zhizhuang Zhao, Chun Chen, Yun Chen

Blood (2025) 146 (Supplement 1): 5010.

https://doi.org/10.1182/blood-2025-5010

Published: 2025

Journal Articles

FLT3L-based conjugate targets chemoresistant leukemia stem cells via cell cycle re-entry in Acute Myeloid Leukemia

Dengyang Zhang, Yao Guo, Zhiyong Peng, Yan Xiao, Zhiguang Chang, Liuting Yu, Yuming Zhao, Qi Zhang, Lingling Ma, Shuping Li, Chi Kong Li, Kam Tong Leung, Zhizhuang Zhao, Chun Chen, Yun Chen

Blood (2025) 146 (Supplement 1): 319.

https://doi.org/10.1182/blood-2025-319

Published: 2025

Journal Articles

PTPN11 copy number gain drives leukemogenesis via mutant SHP2 in juvenile myelomonocytic leukemia

Zhiguang Chang, Zhiyong Peng, Lingling Ma, Yan Xiao, Yao Guo, Dengyang Zhang, Yuming Zhao, Liuting Yu, Junbin Huang, Hongman Xue, Chi Kong Li, Chun Chen, Zhizhuang Zhao, Yun Chen

Blood (2025) 146 (Supplement 1): 3234.

https://doi.org/10.1182/blood-2025-3234

Published: 2025

Journal Articles

Long-acting GM-CSF-based drug conjugate effectively targets leukemia stem cells in Acute Myeloid Leukemia with limited toxicity

Yan Xiao, Yao Guo, Dengyang Zhang, Zhiyong Peng, Yuming Zhao, Zhiguang Chang, Liuting Yu, Lingling Ma, Chi Kong Li, Zhizhuang Zhao, Chun Chen, Yun Chen

Blood (2025) 146 (Supplement 1): 752.

https://doi.org/10.1182/blood-2025-752

Published: 2025

Journal Articles

A prospective study reveals feasibility and merits of drug profiling-guided precision therapy for children with high-risk leukemias

Yaqun Xu, Wing Yan Leung, Han Wang, Kathy Chan, Qiwei Sun, Chi Kong Li, Brian Hon Yin Chung, Frankie Wai Tsoi Cheung, Kam Tong Leung

Blood (2025) 146 (Supplement 1): 5242.

https://doi.org/10.1182/blood-2025-5242

Published: 2025

Journal Articles

Allogeneic hematopoietic stem cell transplantation outcomes in pediatric acute lymphoblastic leukemia: A multicenter analysis from the cccg-ALL-2015 protocol

Blood (2025) 146 (Supplement 1): 6074.

https://doi.org/10.1182/blood-2025-6074

Published: 2025

Journal Articles

CFP1 controls H3K4me3-mediated chromatin architecture to promote v(D)j recombination in early B cell development

Wanyu Bai, Yalin Yang, Yanan Zhao, Junchao Dong, Chi Kong Li, Chun Chen

Blood (2025) 146 (Supplement 1): 629.

https://doi.org/10.1182/blood-2025-629

Published: 2025

Journal Articles

Targeting SP1 condensates suppresses HNRNPUL1 via super-enhancers to attenuate Acute Myeloid Leukemia progression

Yuchen Wen, Chun Chen, Chi Kong Li, Yun Chen

Blood (2025) 146 (Supplement 1): 3267.

https://doi.org/10.1182/blood-2025-3267

Published: 2025

Journal Articles

FBXO7 通过靶向 TMED10 进行泛素介导的降解和激活 wnt 信号传导来促进 T-ALL 的化疗耐药性

zefan du, ouyang cheng, Chi Kong Li, Yun Chen, Chun Chen

Blood (2025) 146 (Supplement 1): 3263.

https://doi.org/10.1182/blood-2025-3263

Published: 2025

Journal Articles

Marstacimab prophylaxis in hemophilia A/B without inhibitors: results from the phase 3 BASIS trial

Davide Matino, Andrew Palladino, Carrie Turich Taylor, Eunhee Hwang, Sangeeta Raje, Satyaprakash Nayak, Regina McDonald, Suchitra S. Acharya, Johnny Mahlangu, Victor Jiménez-Yuste, Nirmalkumar Choraria, Renchi Yang, Chi-kong Li, Murtadha Al-Khabori, Yasser Wali, Javier Morales Adrián, Young-Shil Park, O. Bülent Zülfikar, John Teeter

Blood (2025) 146 (14): 1654–1663.

https://doi.org/10.1182/blood.2024027468

Published: 2025

Includes: Supplemental data

Journal Articles

Prognostic and therapeutic implications of measurable residual disease levels during remission induction of childhood ALL

Blood (2025) 145 (17): 1890–1902.

https://doi.org/10.1182/blood.2024026381

Published: 2025

Includes: Supplemental data

Journal Articles

Male Sex Had an Adverse Impact on Outcomes of Pediatric B-Lineage Acute Lymphoblastic Leukemia

Blood (2024) 144 (Supplement 1): 5868.

https://doi.org/10.1182/blood-2024-210903

Published: 2024

Journal Articles

HDAC Inhibition Rejuvenates Antitumor Immunity in Acute Myeloid Leukemia Via CD9 Transcriptional Reactivation

Yaqun Xu, Kathy Yuen Yee Chan, Qiwei SUN, Yixuan Wu, Siu Ping Fok, Chi Kong Li, Kam Tong Leung

Blood (2024) 144 (Supplement 1): 5730.

https://doi.org/10.1182/blood-2024-209950

Published: 2024

Journal Articles

Single-Cell Transcriptomic Analyses Reveal Distinctive Immune Features between Childhood and Adult Acute Myeloid Leukemia

Qiwei SUN, Kathy Yuen Yee Chan, Chi Kong Li, Kam Tong Leung

Blood (2024) 144 (Supplement 1): 1545.

https://doi.org/10.1182/blood-2024-212221

Published: 2024

Journal Articles

The Kinetics of FLT3L during Induction Chemotherapy for Pediatric Acute Lymphoblastic Leukemia Suggests a Novel Clinical Diagnostic and Treatment Strategy

Wenqing Wang, Yan-lai Tang, Zhen Li, Hao Jiang, Chi-Kong Li, Chun Chen, Yun Chen, Hongman Xue

Blood (2023) 142 (Supplement 1): 5823.

https://doi.org/10.1182/blood-2023-187653

Published: 2023

Journal Articles

Dynamic Oscillation of Tetraspanin CD9 Orchestrates Engraftment and Mobilization of Human Hematopoietic Stem/Progenitor Cells

Wing Hei Ng, Chi Zhang, Han Wang, Kathy Yuen Yee Chan, Chi Kong Li, Kam Tong Leung

Blood (2023) 142 (Supplement 1): 5575.

https://doi.org/10.1182/blood-2023-189365

Published: 2023

Journal Articles

The Tetraspanin CD9 Shapes Glucocorticoid Sensitivity in Pediatric B-Precursor Acute Lymphoblastic Leukemia

Chi Zhang, Kathy Yuen Yee Chan, John Tak Kit Cheung, Wing Hei Ng, Chi Kong Li, Kam Tong Leung

Blood (2023) 142 (Supplement 1): 2973.

https://doi.org/10.1182/blood-2023-189578

Published: 2023

Journal Articles

Prognostic Features of CD9 in Childhood Acute Lymphoblastic Leukemia - a Retrospective Analysis of a Nation-Wide Multicenter Study in China

Kathy Yuen Yee Chan, Jiaoyang Cai, Yu Liu, Jun J. Yang, Ching-Hon Pui, Shuhong Shen, Chi Kong Li, Kam Tong Leung

Blood (2023) 142 (Supplement 1): 2836.

https://doi.org/10.1182/blood-2023-191098

Published: 2023

Journal Articles

The Topoisomerase-I Inhibitor Gimatecan Exhibits Potent and Selective Activities Against B-Cell Precursor Acute Lymphoblastic Leukemia with a Favorable Cardiotoxicity Profile

Han Wang, Kathy Yuen Yee Chan, Po Yi Lee, Chi Zhang, Hung Sing LI, Wai Man Leung, Maxwell Kwok, Po Yee Chung, Wing Hei Ng, John Tak Kit Cheung, Wai Yip Lam, Benjamin Li, Chi Kong Li, Ellen Poon, Kam Tong Leung

Blood (2023) 142 (Supplement 1): 4252.

https://doi.org/10.1182/blood-2023-189498

Published: 2023

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Risk factors and outcomes of asparaginase-associated pancreatitis in pediatric patients with ALL

PI3Kδ inhibition enhances trametinib efficacy by suppressing feedback-activated PI3K/AKT signaling in PTPN11-mutant JMML

FLT3L-based conjugate targets chemoresistant leukemia stem cells via cell cycle re-entry in Acute Myeloid Leukemia

PTPN11 copy number gain drives leukemogenesis via mutant SHP2 in juvenile myelomonocytic leukemia

Long-acting GM-CSF-based drug conjugate effectively targets leukemia stem cells in Acute Myeloid Leukemia with limited toxicity

A prospective study reveals feasibility and merits of drug profiling-guided precision therapy for children with high-risk leukemias

Allogeneic hematopoietic stem cell transplantation outcomes in pediatric acute lymphoblastic leukemia: A multicenter analysis from the cccg-ALL-2015 protocol

CFP1 controls H3K4me3-mediated chromatin architecture to promote v(D)j recombination in early B cell development

Targeting SP1 condensates suppresses HNRNPUL1 via super-enhancers to attenuate Acute Myeloid Leukemia progression

FBXO7 通过靶向 TMED10 进行泛素介导的降解和激活 wnt 信号传导来促进 T-ALL 的化疗耐药性

Marstacimab prophylaxis in hemophilia A/B without inhibitors: results from the phase 3 BASIS trial

Prognostic and therapeutic implications of measurable residual disease levels during remission induction of childhood ALL

Male Sex Had an Adverse Impact on Outcomes of Pediatric B-Lineage Acute Lymphoblastic Leukemia

HDAC Inhibition Rejuvenates Antitumor Immunity in Acute Myeloid Leukemia Via CD9 Transcriptional Reactivation

Single-Cell Transcriptomic Analyses Reveal Distinctive Immune Features between Childhood and Adult Acute Myeloid Leukemia

The Kinetics of FLT3L during Induction Chemotherapy for Pediatric Acute Lymphoblastic Leukemia Suggests a Novel Clinical Diagnostic and Treatment Strategy

Dynamic Oscillation of Tetraspanin CD9 Orchestrates Engraftment and Mobilization of Human Hematopoietic Stem/Progenitor Cells

The Tetraspanin CD9 Shapes Glucocorticoid Sensitivity in Pediatric B-Precursor Acute Lymphoblastic Leukemia

Prognostic Features of CD9 in Childhood Acute Lymphoblastic Leukemia - a Retrospective Analysis of a Nation-Wide Multicenter Study in China

The Topoisomerase-I Inhibitor Gimatecan Exhibits Potent and Selective Activities Against B-Cell Precursor Acute Lymphoblastic Leukemia with a Favorable Cardiotoxicity Profile

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