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Caroline McNamara
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Journal Articles

Safety and efficacy of the mutant calreticulin-specific monoclonal antibody INCA033989 as monotherapy or in combination with ruxolitinib in patients (pts) with myelofibrosis (MF): Preliminary results from dose escalation of two global Phase 1 studies

Free
John Mascarenhas, Haifa Kathrin Al-Ali, Vikas Gupta, Haris Ali, Francesca Palandri, Professor Francesco Passamonti, Raajit Rampal, Aaron Gerds, Tania Jain, Sanjay Mohan, Steffen Koschmieder, Caroline McNamara, Andrew Perkins, Bethan Psaila, Vincent Ribrag, William Shomali, Rosa Ayala Diaz, Mikkel Helleberg Dorff, Claire Harrison, Stephen Oh, Frank Stegelmann, Alessandro Maria Vannucchi, Abdulraheem Yacoub, Jason Gotlib, Jyoti Nangalia, Chenwei Tian, Betty Lamothe, Erin Crowgey, Tatiana Zinger, Evan Braunstein, David Ross
Journal: Blood
Blood (2025) 146 (Supplement 1): 484.
https://doi.org/10.1182/blood-2025-484
Published: 2025
Journal Articles

Safety and efficacy of INCA033989, a novel first in class mutant calreticulin-specific monoclonal antibody, in patients with essential thrombocythemia

Free
Vikas Gupta, John Mascarenhas, Haris Ali, David Ross, Abdulraheem Yacoub, Tania Jain, Lynette Chee, Aaron Gerds, Jean-Jacques Kiladjian, Ruben Mesa, William Shomali, Makoto Yoshimitsu, Rosa Ayala Diaz, Chi-Joan How, Steffen Koschmieder, Caroline McNamara, Yosuke Nakaya, Francesca Palandri, Professor Francesco Passamonti, Andrew Perkins, Bethan Psaila, Raajit Rampal, Natasha Szuber, Frank Stegelmann, Alessandro Maria Vannucchi, Hiroki Yamaguchi, Jason Gotlib, Jyoti Nangalia, Chenwei Tian, Betty Lamothe, Erin Crowgey, Tatiana Zinger, Evan Braunstein, Claire Harrison
Journal: Blood
Blood (2025) 146 (Supplement 1): 1024.
https://doi.org/10.1182/blood-2025-1024
Published: 2025
Journal Articles

Single Cell Genotype-Phenotype Analysis Demonstrates That Post-MPN AML Is Driven By Clonal Evolution and Loss of Transcriptional Heterogeneity within Stem Cell Compartments

Free
Jasmin Straube, Julian Grabek, Leanne Cooper, Rohit Haldar, Caroline McNamara, David M Ross, Andrew Perkins, Megan Bywater, Steven W Lane
Journal: Blood
Blood (2024) 144 (Supplement 1): 1346.
https://doi.org/10.1182/blood-2024-199841
Published: 2024
Journal Articles

The LSC17 Score Correlates with the ELN 2022 Classification of AML and Is an Independent Predictor of Detectable Measurable Residual Disease after Induction Chemotherapy

Free
Tracy Murphy, Stanley W.K. Ng, Ian King, Tong Zhang, Andrea Arruda, Jaime Claudio, Kristele Pan, Chantal Rockwell, Zhibin Lu, Natalie Stickle, Carl Virtanen, Vikas Gupta, Dawn Maze, Caroline McNamara, Aaron D. Schimmer, Andre C. Schuh, Hassan Sibai, Karen Yee, Dina Khalaf, Brian Leber, Mitchell Sabloff, Anne Tierens, Mark D. Minden, Tracy L. Stockley, Steven Chan, Jean C.Y. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9122–9124.
https://doi.org/10.1182/blood-2022-171107
Published: 2022