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Andrius Zucenka
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Journal Articles

Hypomethylating agents or chemotherapy in combination with venetoclax and gilteritinib for FLT3-mutated Acute Myeloid Leukemia

Free
Andrius Zucenka, Milda Mikalonyte, Tautvile Smalinskaite, Lukas Kevlicius, Guoda Daukelaite, Regina Pileckyte, Linas Davainis, Birute Davainiene, Igoris Trociukas, Rita Cekauskiene, Valdas Peceliunas, Laimonas Griškevičius
Journal: Blood
Blood (2025) 146 (Supplement 1): 1679.
https://doi.org/10.1182/blood-2025-1679
Published: 2025
Journal Articles

Bleximenib or placebo in combination with standard induction and consolidation therapy followed by maintenance for the treatment of patients with newly diagnosed KMT2A-rearranged or NPM1-mutant Acute Myeloid Leukemia eligible for intensive chemotherapy: A double-blind Phase 3 study (HOVON 181 AML / AMLSG 37-25)

Free
Marc Raaijmakers, Hartmut Döhner, Dimitri Breems, John Byrd, Konstanze Döhner, Jordi Esteve, Bjørn Gjertsen, Patrycja Gradowska, Gerwin A. Huls, Ain Kaare, Heeje Kim, Hitoshi Kiyoi, Mika Kontro, Janusz Krawczyk, Vladimir Lazarevic, Andrea Lenartova, Alice Mims, Jeannine Refos, Christoph Röllig, Anika Schrade, Karolina Sikorska, Alexandre Theocharides, Peter Valk, Adriano Venditti, Jianxiang Wang, Andrew Wei, Agnieszka Wierzbowska, Andrius Zucenka, Lucille Ferrante, Christina Drenberg Guttke, Angélique Langlois, Christina Loefgren, Kathryn Packman, Prathap Nagaraja Shastri, Natasha Schuier, Meena Thayu, Danielle Trancucci, Bob Lowenberg, Lars Bullinger
Journal: Blood
Blood (2025) 146 (Supplement 1): 1654.
https://doi.org/10.1182/blood-2025-1654
Published: 2025
Journal Articles

Revumenib for patients with relapsed or refractory (R/R) KMT2Ar acute leukemia: Outcomes by leukemia type in the phase 2 AUGMENT-101 study

Free
Ibrahim Aldoss, Ghayas Issa, James Blachly, Michael Thirman, Gabriel Mannis, Martha Arellano, John DiPersio, Elie Traer, C. Zwaan, Neerav Shukla, Branko Cuglievan, Carolyn Grove, Matthew Greenwood, Christine McMahon, Alexander Perl, Richard Stone, Cristina Papayannidis, David Dickens, Mael Heiblig, Andrius Zucenka, Pau Montesinos, Ioannis Mantzaris, Tibor Kovacsovics, Paul Shami, Li Yu, Rebecca Bagley, Angela R. Smith, Eytan Stein
Journal: Blood
Blood (2025) 146 (Supplement 1): 1001.
https://doi.org/10.1182/blood-2025-1001
Published: 2025
Journal Articles

Revumenib for patients with relapsed or refractory (R/R) Nucleophosmin 1–Mutated (NPM1m) Acute Myeloid Leukemia (AML): Outcomes by prior treatment in the phase 2 AUGMENT-101 study

Free
Martha Arellano, Michael Thirman, John DiPersio, Mael Heiblig, Eytan Stein, Andre Schuh, Andrius Zucenka, Stephane De Botton, Carolyn Grove, Gabriel Mannis, Cristina Papayannidis, Alexander Perl, Ghayas Issa, Ibrahim Aldoss, Ashish Bajel, David Dickens, Michael Kühn, Ioannis Mantzaris, Emmanuel Raffoux, Elie Traer, Irina Amitai, Hartmut Döhner, Corinna Greco, Tibor Kovacsovics, Christine McMahon, Pau Montesinos, Arnaud Pigneux, Paul Shami, Richard Stone, Ofir Wolach, John Harpel, Yakov Chudnovsky, Li Yu, Rebecca Bagley, Angela R. Smith, James Blachly
Journal: Blood
Blood (2025) 146 (Supplement 1): 3418.
https://doi.org/10.1182/blood-2025-3418
Published: 2025
Journal Articles

Redefining the myeloid disease continuum: Machine learning–based development and validation of an integrated multimodal classification of myeloid neoplasms

Free
Yu-Hung Wang, Kristian Gurashi, Chien-Chin Lin, Carmelo Gurnari, Hussein Awada, Adrian Mosquera, Manuel Perez Encinas, Donal McLornan, Andrius Zucenka, Talha Badar, Bor-Sheng Ko, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Jaroslaw Maciejewski, Nick Telford, Kiran Batta, Daniel Wiseman
Journal: Blood
Blood (2025) 146 (Supplement 1): 4347.
https://doi.org/10.1182/blood-2025-4347
Published: 2025
Journal Articles

Conditioning with alkylating agents, cytarabine, cladribine, hypomethylating agents, and venetoclax (ARCHIVE) for upfront allogeneic stem cell transplantation in patients with active Acute Myeloid Leukemia or myelodysplastic syndrome with increased blasts-2

Free
Andrius Zucenka, Lukas Kevlicius, Tautvile Smalinskaite, Guoda Daukelaite, Milda Mikalonyte, Igoris Trociukas, Linas Davainis, Arturas Slobinas, Rita Cekauskiene, Renata Jucaitiene, Inga Slepikiene, Adomas Bukauskas, Vaida Jaramine, Juste Strumskyte, Antanas Griskevicius, Arturas Jakubauskas, Valdas Peceliunas, Laimonas Griškevičius
Journal: Blood
Blood (2025) 146 (Supplement 1): 2415.
https://doi.org/10.1182/blood-2025-2415
Published: 2025
Journal Articles

Detection of KMT2A fusion transcripts after induction chemotherapy is strongly predictive of outcome in KMT2A rearranged AML: Results of an international collaborative study

Free
Jad Othman, Hsin-An Hou, Nicola Potter, Hannah Al-Yousuf, Pablo Prieto-Martinez, John Chadwick, Marzia Rahman, Sun Loo, Wen-Chien Chou, Yu-Sung Chang, Ing Tiong, Rea Grace Maamari, Hans Ommen, Robert Baker, Adam Ivey, Jelena Jovanovic, Manohursingh Runglall, Raminta Batiuskaite, Tautvile Smalinskaite, Joanna Canham, Ian Thomas, Sean Johnson, Amanda Gilkes, Alan Burnett, Andrius Zucenka, Pramila Krishnamurthy, Andrew Wei, Mike Dennis, Jenny O'Nions, Nigel Russell, Richard Dillon
Journal: Blood
Blood (2025) 146 (Supplement 1): 346.
https://doi.org/10.1182/blood-2025-346
Published: 2025
Journal Articles

Menin inhibition with revumenib for NPM1 -mutated relapsed or refractory acute myeloid leukemia: the AUGMENT-101 study

Open Access
Clinical Trials & Observations
Martha L. Arellano, Michael J. Thirman, John F. DiPersio, Maël Heiblig, Eytan M. Stein, Andre C. Schuh, Andrius Žučenka, Stephane de Botton, Carolyn S. Grove, Gabriel N. Mannis, Cristina Papayannidis, Alexander E. Perl, Ghayas C. Issa, Ibrahim Aldoss, Ashish Bajel, David S. Dickens, Michael W. M. Kühn, Ioannis Mantzaris, Emmanuel Raffoux, Elie Traer, Irina Amitai, Hartmut Döhner, Corinna Greco, Tibor Kovacsovics, Christine M. McMahon, Pau Montesinos, Arnaud Pigneux, Paul J. Shami, Richard M. Stone, Ofir Wolach, John G. Harpel, Yakov Chudnovsky, Li Yu, Rebecca G. Bagley, Angela R. Smith, James S. Blachly
Journal: Blood
Blood (2025) 146 (9): 1065–1077.
https://doi.org/10.1182/blood.2025028357
Published: 2025
Includes: Supplemental data
Journal Articles

Frontline Sequential Allogeneic Stem Cell Transplantation for Newly Diagnosed Acute Myeloid Leukemia with 3q26.2/ Mecom Rearrangement

Free
Andrius Žučenka, Lukas Kevličius, Linas Davainis, Igoris Trociukas, Rita Čekauskienė, Vaida Jaraminė, Justė Strumskytė, Raminta Batiuškaitė, Rimvydas Norvilas, Vilma Valčeckienė, Vaidas Dirsė, Eglė Gineikienė-Valentinė, Artūras Jakubauskas, Laimonas Griškevičius
Journal: Blood
Blood (2024) 144 (Supplement 1): 7319.
https://doi.org/10.1182/blood-2024-208585
Published: 2024
Journal Articles

Individualized Sequential Allogeneic Stem Cell Transplantation for Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome Patients with Active Disease

Free
Andrius Zucenka, Lukas Kevličius, Tautvilė Smalinskaitė, Guoda Daukėlaitė, Linas Davainis, Igoris Trociukas, Artūras Slobinas, Renata Jucaitienė, Inga Šlepikienė, Rita Čekauskienė, Vaida Jaraminė, Justė Strumskytė, Artūras Jakubauskas, Laimonas Griškevičius
Journal: Blood
Blood (2024) 144 (Supplement 1): 3487.
https://doi.org/10.1182/blood-2024-203229
Published: 2024
Journal Articles

Detection of B Cell Lymphomas By a Simple Epigenetic Blood Test

Free
Irit Mazza Avivi, Miriam Neaman, Noa Lowenton-Spier, Chava Perry, Erel Joffe, Roy Vitkon, Vlada Bogol, Yael Michaeli, Noa Gilat, Lynne Itelson, Shahar Zirkin, Jasline Deek, Efstathios Kastritis, Karolis Sablauskas, Skirmante Cernauskiene, Vilmantė Vaitekėnaitė, Andrius Zucenka, Tomas Papajik, Eva Kriegova, Petr Gajdos, Yuval Ebenstein
Journal: Blood
Blood (2024) 144 (Supplement 1): 1582.
https://doi.org/10.1182/blood-2024-207707
Published: 2024
Journal Articles

Venetoclax-Based Therapy Versus Intensive Chemotherapy Followed By Allogeneic-Stem Cell Transplantation for High-Risk Elderly Acute Myeloid Leukemia

Free
Alexandre Iat, Jan Philipp Bewersdorf, Julia Gilhodes, Yiwen Liu, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Rebecca P. Bystrom, Daniel J. DeAngelo, Guillaume Berton, Amel Soua, Kelly Ling, Luis E. Aguirre, Richard M Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Evan C. Chen, Martha Wadleigh, Aaron D. Goldberg, Amer M. Zeidan, Thomas Cluzeau, Shai O. Shimony, Maximilian Stahl, Sylvain Garciaz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1508.
https://doi.org/10.1182/blood-2024-207045
Published: 2024
Journal Articles

The Prognostic and Predictive Value of RUNX1 Mutations in Newly Diagnosed Acute Myeloid Leukemia - an International Multicenter Cohort Study

Free
Rebecca P. Bystrom, Jan Philipp Bewersdorf, Yiwen Liu, Eva Johanna Schaefer, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Sylvain Garciaz, Luis E. Aguirre, Daniel J. DeAngelo, Richard M. Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Evan C. Chen, Martha Wadleigh, Kelly Ling, Eytan M. Stein, Aaron D. Goldberg, Amer M. Zeidan, Shai O. Shimony, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 2947.
https://doi.org/10.1182/blood-2024-205581
Published: 2024
Journal Articles

Updated Results and Longer Follow-up from the AUGMENT-101 Phase 2 Study of Revumenib in All Patients with Relapsed or Refractory (R/R) KMT2Ar Acute Leukemia

Free
Ibrahim Aldoss, Ghayas C. Issa, James S. Blachly, Michael J. Thirman, Gabriel N Mannis, Martha L. Arellano, John F. DiPersio, Elie Traer, C. Michel Zwaan, Neerav Shukla, Branko Cuglievan, Carolyn S. Grove, Matthew Greenwood, Christine M. McMahon, Alexander E. Perl, Richard M. Stone, Cristina Papayannidis, David S. Dickens, Maël Heiblig, Andrius Žučenka, Pau Montesinos, Ioannis Mantzaris, Tibor Kovacsovics, Paul J. Shami, Li Yu, Rebecca G. Bagley, Nicole McNeer, Eytan M. Stein
Journal: Blood
Blood (2024) 144 (Supplement 1): 211.
https://doi.org/10.1182/blood-2024-194384
Published: 2024
Journal Articles

Comparative Analysis of Outcomes with HMA Plus Venetoclax Vs Intensive Chemotherapy in AML Patients Harboring Very-High Risk Cytogenetics

Free
Luis E. Aguirre, Jan Philipp Bewersdorf, Yiwen Liu, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Sylvain Garciaz, Rebecca P. Bystrom, Daniel J. DeAngelo, Richard M. Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Kelly Ling, Evan C. Chen, Martha Wadleigh, Eytan M. Stein, Aaron D. Goldberg, Amer M. Zeidan, Shai O. Shimony, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4267.
https://doi.org/10.1182/blood-2024-202744
Published: 2024
Journal Articles

Targeted, Low Cost Epigenetic Microarray for AML and MDS Detection

Free
Miriam Neaman, Mika Bell, Jasline Deek, Rita Haldar, Amit Manor, Yakir Moshe, Irit Mazza Avivi, Moshe Mittelman, Roy Vitkon, Mor Levi, Roi Gat, Gil Fridberg, Natalia Birov, Guoda Daukėlaitė, Karolis Sablauskas, Andrejus Černovas, Andrius Zucenka, Vilmantė Vaitekėnaitė, Efstathios Kastritis, Tomas Papajik, Eva Kriegova, Martin Cernan, Tereza Dyskova, Yuval Ebenstein
Journal: Blood
Blood (2024) 144 (Supplement 1): 6142.
https://doi.org/10.1182/blood-2024-208540
Published: 2024
Journal Articles

Incorporating TET2 Variant Allele Frequency Enhances Prognostication in CMML: Insights from 849 Patients across Multiple Institutions

Free
Yu-Hung Wang, Dorothée Selimoglu-Buet, Carmelo Gurnari, Andres Jerez, Andrius Zucenka, Chi-Yuan Yao, Chien-Chin Lin, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Jaroslaw Maciejewski, Eric Solary, Kiran Batta, Daniel H Wiseman
Journal: Blood
Blood (2024) 144 (Supplement 1): 4579.
https://doi.org/10.1182/blood-2024-194319
Published: 2024
Journal Articles

Outcomes with HMA Plus Venetoclax Vs Intensive Chemotherapy in AML Patients with Chromosome 5 and 7 Abnormalities

Free
Leora Boussi, Jan Philipp Bewersdorf, Yiwen Liu, Rory M. Shallis, Luis E. Aguirre, Andrius Zucenka, Sylvain Garciaz, Rebecca P. Bystrom, Daniel J. DeAngelo, Richard M Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Evan Chen, Martha Wadleigh, Kelly Ling, Amer M. Zeidan, Aaron D. Goldberg, Eytan M. Stein, Shai O. Shimony, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4281.
https://doi.org/10.1182/blood-2024-204467
Published: 2024
Journal Articles

Revumenib Maintenance Therapy Following Revumenib-Induced Remission and Transplant

Free
Andrius Zucenka, Ghayas C. Issa, Martha Arellano, Sajad Khazal, Nandita Khera, Wendy Stock, Branko Cuglievan, Yu Gu, Huy Van Nguyen, Angela R. Smith, Eytan M. Stein
Journal: Blood
Blood (2023) 142 (Supplement 1): 4950.
https://doi.org/10.1182/blood-2023-189036
Published: 2023
Journal Articles

Real-World Comparison of Venetoclax-Based Treatment Versus Intensive Chemotherapy As Bridging to Allogeneic Stem Cell Transplantation in MDS-IB2 Patients

Free
Andrius Zucenka, Birutė Davainienė, Vilmantė Vaitekėnaitė, Rūta Čepulytė, Linas Davainis, Guoda Daukėlaitė, Lukas Kevličius, Regina Pileckytė, Igoris Trociukas, Laimonas Griškevičius
Journal: Blood
Blood (2023) 142 (Supplement 1): 6474.
https://doi.org/10.1182/blood-2023-178611
Published: 2023